Peter Savage1

  • 1Department of Pathology, University of Chicago, Chicago, IL, USA.

Science (New York, N.Y.)
|November 21, 2024
PubMed
概括

瘤相关的巨细胞发出信号, 帮助瘤逃避免疫系统. 这些信息促进免疫抑制,阻碍抗瘤反应.

相关概念视频

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.5K