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Updated: Jun 7, 2025

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
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Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

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补充激活在IgM M-蛋白相关神经病变中的作用

Johannes P M van de Mortel1, Kevin Budding1, Kim Dijkxhoorn1

  • 1From the Department of Neurology and Neurosurgery (J.P.M.M., A.F.J.E.V., N.C.N., W.L.v.d.P.), UMC Utrecht Brain Center; Center for Translational Immunology (K.B., K.D.); Department of Hematology (M.C.M.), University Medical Center Utrecht, Utrecht University, The Netherlands.

Neurology(R) neuroimmunology & neuroinflammation
|November 21, 2024
PubMed
概括

在IgM相关的多神经病变中,抗MAG抗体水平与补体激活相关. 然而,这种激活与疾病严重程度没有很强的相关性,限制了补充抑制剂的治疗使用.

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