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在巴尔的摩的Candida auris污水监测

Daniel A Nwaubani¹, Rakshya Baral¹, Tamunobelema Solomon¹

¹Center of Research Excellence in Wastewater based Epidemiology, Morgan State University, Baltimore, MD, 21251, USA.

International journal of hygiene and environmental health

|November 21, 2024

概括

在巴尔的摩的废水中检测到Candida auris,春季的水平更高. 废水监测可以帮助预测和管理有关真菌病原体的未来爆发.

科学领域:

环境微生物学环境微生物学
公共卫生监督是对公共卫生的监督.
菌类学菌类学是指菌类学.

背景情况:

黄是一种新兴的全球健康威胁,原因是其高死亡率,抗真菌耐药性和在医疗环境中的持久性.
废水监测为监测公共卫生威胁提供了一种潜在的方法.

研究的目的:

调查巴尔的摩废水中Candida auris的存在和流行情况.
评估废水检测与C. auris.临床病例之间的相关性.
评估废水监测作为C. auris.的早期预警系统.

主要方法:

在47周内,从两个废水处理厂 (WWTP-A和WWTP-B) 收集了110个主要影响样本.
在过的废水样本中对C. auris进行定量聚合酶连锁反应 (qPCR) 分析.
包括皮尔森相关性在内的统计分析,以将废水数据与临床病例数量进行比较.

主要成果:

在11.81%的有影响的样本中检测到Candida auris,在WWTP-B.中检测率更高.
废水度在每升1.2至7.9log10基因拷贝之间.
在废水中C. auris水平和临床病例之间观察到微弱的正相关性 (r=0.27).
在春季季节,人们注意到C. auris的存在增加.

结论:

这是巴尔的摩废水中检测到Candida auris的第一份报告.
废水监测可以为C. auris的流行和动态提供宝贵的见解.
废水监测是早期发现和管理C. auris疫情的补充工具.

关键词:

巴尔的摩巴尔的摩巴尔的摩巴尔的摩它们是Candida auris.废水是废水,废水就是废水.qPCRR 是一个很好的方法.

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