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Updated: Jun 6, 2025

Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders
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缓冲剂对喷雾冷干燥/冷化高度蛋白质配方的作用

Chanakya D Patil1, Tarun Tejasvi Mutukuri2, Kinnari Santosh Arte1

  • 1Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.

International journal of pharmaceutics
|November 21, 2024
PubMed
概括

缓冲剂的选择显著影响固体配方中的蛋白质稳定性. 酸盐和氨酸缓冲剂导致冷解牛血清白蛋白 (BSA) 配方的不稳定性增加,表明需要仔细选择缓冲剂.

关键词:
阿尔吉尼因 (Arginine) 是一种素.缓冲器缓冲器是一个缓冲器.高度蛋白质配方 高度蛋白质配方希斯蒂迪因 (Histidine) 是一种胺.软化液化化是什么意思喷雾冷干燥的喷雾方式

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