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对比增强的CISS/FIESTA成像用于增加Cushing病下垂体微腺瘤在Cushing病中的共性

Ian T Mark¹, Jamie Van Gompel², Maria Peris Celda²

¹From the Department of Radiology (I.T.M., E.S., J.L., D.R.J., S.A.M.), Mayo Clinic, Rochester, Minnesota Mark.Ian@mayo.edu.

AJNR. American journal of neuroradiology

|November 21, 2024

概括

与对比度增强的CISS/FIESTA-C MRI 序列显著改善了库辛病患者垂体小腺瘤的检测和可视化. 这种先进的成像技术与标准的T1加权MRI相比,提供了更高的可见性.

科学领域:

放射学放射学是一门学科.
内分泌学在内分泌学.
神经外科神经外科

背景情况:

下垂体微腺瘤很难在MRI上检测到,特别是当它们很小时.
准确的检测对于库辛病的管理至关重要,因为手术是标准治疗方法.
腺瘤的手术前定位直接影响手术结果.

研究的目的:

为了评估对比度增强的CISS/FIESTA与自行车 (FIESTA-C) 的有效性,用于识别患有库辛病的患者的垂体小腺瘤.
为了比较FIESTA-C的诊断实用性与标准T1加权MRI序列.

主要方法:

回顾从接受后对照CISS/FIESTA-C.Cushing病患者的垂体MRI图像的回顾性审查.
评估病变明显性 (边缘) 和腺瘤和垂体腺体的信号强度 (SI).
计算标准化SI差异和与诊断结果的相关性.

主要成果:

在CISS/FIESTA-C中,发现了94%的腺瘤,而在T1加权成像中,这一比例为65%.
平均正常化SI差异在FIESTA-C (0.512) 显著高于T1加权成像 (0.242).
在FIESTA-C.上,十七种腺瘤中有十六种是离散的.

结论:

与标准T1加权MRI相比,对比增强的CISS/FIESTA-C成像检测到更多的垂体腺瘤,并且具有更好的显着性.
这种技术对于库辛病患者来说可能特别有价值,因为高达50%的患者在传统的MRI上可能不会显示出可检测的病变.
FIESTA-C可以作为一个有价值的额外序列,以改善手术前定位.

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