与年轻成年人相比,在典型的发育儿童中,通过骨直流刺激的失明受到损害
Sophia Bertrand1, Tonya Rich2,3, Samuel Nemanich1
1Department of Occupational Therapy, Marquette University, Milwaukee, WI, USA.
The European journal of neuroscience
|November 21, 2024
概括
在跨直流刺激 (tDCS) 试验中,儿童与失明作斗争,比成年人更经常报告假刺激是真实的. 这凸显了在儿科研究中需要改进盲目的方法的需要.
科学领域:
- 神经科学是一个神经科学.
- 临床试验 临床试验
- 儿科研究 儿科研究
背景情况:
- 在跨直流刺激 (tDCS) 临床试验中对盲目的治疗具有挑战性,特别是在儿科患者群体中.
- 儿童独特的感官体验可能会增加对偏差的敏感性,而偏差来自不充分的盲目.
研究的目的:
- 为了比较儿童和年轻人的tDCS盲目的成功.
- 为了评估ActiSham协议与盲目的传统假协议的有效性.
- 评估感官灵敏度和失明精度之间的关系.
主要方法:
- 典型的发育儿童和年轻人接受了单次会议tDCS与Active,Sham和ActiSham条件.
- 参与者报告了感知到的刺激类型 (真实/虚假) 和后条件的信心.
- 感官敏感性是用感官概况 (第二版) 来测量的.
主要成果:
- 儿童和年轻人均正确识别了活性刺激.
- 孩子们错误地将Sham和ActiSham视为真正的刺激.
- 年轻的成年人在机会级别上识别了Sham和ActiSham,这表明更好的盲目.
- 失明精度与感官灵敏度没有相关性.
- 儿童报告说,在各种条件下,他们对接受真实刺激的信心更高.
结论:
- 目前的假冒协议不足以在tDCS研究中使儿童失明.
- 与年轻成年人相比,儿童的失明精度较差,对感知刺激的信心更高.
- 需要进一步的研究来开发和验证为儿科tDCS试验改进的失明策略.
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