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Updated: Jun 6, 2025

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在结直肠癌中,DUSP6调节了Notch1信号传递

Chin Wen Png1,2,3, Madhushanee Weerasooriya1,2,3, Heng Li1,2,3

  • 1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117545, Singapore.

Nature communications
|November 21, 2024
PubMed
概括

双特异性酸酶6 (DUSP6) 解Notch1,稳定其细胞内域 (NTM) 并促进结直肠癌 (CRC) 细胞生长. 抑制DUSP6可能为CRC提供治疗策略.

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