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Updated: Jun 6, 2025

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization
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Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization

Published on: October 6, 2019

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IRF5通过不同的机制控制血细胞生成和抗体产生,这取决于抗原触发器

Bharati Matta1,2, Jenna Battaglia1, Margaret Lapan1

  • 1Center for Autoimmune Musculoskeletal and Hematopoietic Disease, The Feinstein Institutes for Medical Research, Manhasset, New York, USA.

Immunology
|November 22, 2024
PubMed
概括

干扰素调节因子5 (IRF5) 在与系统性红斑狼 (SLE) 相关的免疫激活途径中起着特定的作用. 在小鼠中,IRF5缺乏会通过特异的机制降低TLR9依赖性和T细胞依赖性免疫反应中的抗体产生.

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