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Updated: Jun 6, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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γδ T 细胞介导的瘤免疫力受到STING和TGF-β信号通路的严格调节

Jing Luo1,2,3,4, Shengli Wang1,2,3, Quanli Yang1,2,3

  • 1Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, 519000, P. R. China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 22, 2024
PubMed
概括

在玛三角T细胞中激活STING通路促进了早期瘤监测. 然而,TGF-β在晚期瘤中抑制了STING,因此需要结合TGF-β抑制和STING激动剂来进行有效的癌症免疫疗法.

关键词:
欧姆斯 (Eomes) 是一个欧姆斯.国际货币基金组织-γγ刺痛是一种刺痛.瘤免疫力 免疫力γδ T 细胞的 T 细胞

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