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Updated: Jun 6, 2025

Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
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Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit

Published on: June 28, 2013

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BFVD - 预测病毒蛋白结构的大型存储库

Rachel Seongeun Kim1,2, Eli Levy Karin3, Milot Mirdita2

  • 1Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.

Nucleic acids research
|November 22, 2024
PubMed
概括

大奇幻病毒数据库 (BFVD) 通过提供351,242个预测的病毒蛋白质结构来扩大蛋白质结构研究. 这种独特的资源为研究病毒,特别是菌体提供了新的途径,通过改进现有的预测并揭示新的结构.

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A Protocol for Computer-Based Protein Structure and Function Prediction16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

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相关概念视频

Protein Organization01:24

Protein Organization

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Leaky Scanning

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Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
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Viral Structure

Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
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Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
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