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加速度计测量不规则睡眠时间与老年人身体质量指数的纵向变化之间的联系
Sina Kianersi1,2, Kaitlin S Potts1, Heming Wang1
1Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
medRxiv : the preprint server for health sciences
|November 22, 2024
概括
通过加速度计测量不规则的睡眠时间与增加的体重指数 (BMI) 和更高的肥胖风险有关. 解决睡眠不规则问题可能是打击肥胖的新策略.
科学领域:
- 睡眠科学 睡眠科学
- 代谢健康 代谢健康
- 肥胖研究的研究.
背景情况:
- 不规则的睡眠时间可能会扰乱昼夜节律,导致代谢,行为和情绪变化.
- 这些变化可能会增加肥胖的风险.
- 关于睡眠时间不规则和体重变化之间的关系的定量数据有限.
研究的目的:
- 调查不规则睡眠时间与身体质量指数 (BMI) 变化以及患肥胖的风险之间的联系.
- 量化睡眠时间变化和体重变化之间的关系在一个大前景队列中.
主要方法:
- 一项前性研究分析了来自10572名英国生物库参与者的数据 (平均年龄:63岁).
- 使用加速度计测量一个星期的睡眠时间 (2013-2015).
- 不规则的睡眠持续时间通过7晚睡眠持续时间的人体标准偏差 (SD) 来评估;BMI测量两次,间隔约2.5年.
主要成果:
- 睡眠持续时间较长的参与者SD (>60分钟vs<=30分钟) 显示0.24公斤/米2更高的BMI变化 (标准化为3年间隔).
- 这些参与者患肥胖的风险高出80%.
- 在调整了社会人口统计因素,轮班工作,生活方式,并发病症和其他睡眠因素后,关联仍然显著;年龄,性别,基线BMI或遗传倾向没有显著的修改.
结论:
- 不规则的睡眠时间与增加的BMI变化和患肥胖的风险更高有关.
- 这些发现表明,针对睡眠不规则的干预措施可以为预防肥胖提供新的公共卫生策略.
- 鉴于睡眠不规则的普遍性,对有针对性的干预措施的进一步研究是有必要的.
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