在肋骨骨折损伤后,社区的阿片类药物处方:CODI研究
Frances Williamson1,2,3, Melanie Proper4, Rania Shibl5
1Trauma Service, Metro North Health, Royal Brisbane & Women's Hospital, Herston, QLD, Australia.
British journal of pain
|November 22, 2024
概括
肋骨骨折后的阿片类药物处方通常会延长,特别是在年长的女性身上. 以前的阿片类药物使用显著增加了这些患者长期使用和更高剂量的风险.
科学领域:
- 疼痛管理 疼痛管理
- 药物监督 药物监督 药物监督
- 流行病学 流行病学
背景情况:
- 肋骨骨折疼痛经常需要住院护理和阿片类止痛药.
- 对于肋骨骨折患者的解药后阿片类药物处方模式的理解是有限的.
- 长期使用阿片类药物具有已知的风险,需要对处方趋势进行调查.
研究的目的:
- 调查肋骨骨折患者医院出院后阿片类药物处方的持续时间和剂量.
- 在这个人群中确定与长时间的阿片类药物开放和增加的阿片类药物最终剂量相关的因素.
主要方法:
- 分析了澳大利亚昆士兰州 (2014-2015) 住院患有肋骨骨折的成年患者的一项回顾性队列研究.
- 数据包括住院,死亡率和社区阿片类药物发行记录,直到出院后720天.
- 使用多变量逻辑回归来确定与长时间 (>90天) 和增加终端剂量阿片类药物使用相关的因素.
主要成果:
- 超过一半 (58.8%) 的患者在出院后30天内接受了社区阿片类药物处方.
- 23.6%的人经历了长时间的开药,而13.7%的人增加了阿片类药物的最终剂量.
- 在受伤前使用阿片类药物 (OR=12.00),女性性别 (OR=1.75) 和年龄较大 (OR=1.86) 与长时间使用阿片类药物有显著联系.
结论:
- 对肋骨骨折的阿片类药物处方超过了典型的恢复期,特别是在老年女性中.
- 以前的阿片类药物使用是骨折后长期和高剂量阿片类药物消费的强有力的预测因素.
- 需要个性化策略和卫生系统方法来缓解风险患者长期使用阿片类药物.
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