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Mads Lamm Larsen^1,2, Anne Voss³, Christoffer Tandrup Holst Nielsen⁴

¹Afdelingen for Led- og Bindevævssygdomme, Aarhus Universitetshospital.

Ugeskrift for laeger

|November 22, 2024

概括

化学抗原受体T细胞 (CAR-T) 疗法对自身免疫性类风湿性疾病具有前景. 早期数据表明,CD19 CAR-T疗法对于严重的,耐治疗的病例是有效和安全的.

科学领域:

免疫学免疫学免疫学
类风湿病学类风湿病学
细胞疗法细胞疗法

背景情况:

系统性自身免疫性类风湿性疾病带来了重大治疗挑战.

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对于严重的,耐火病例,需要新的治疗策略.

结论:

CD19 CAR-T疗法有可能在风湿病学中得到确立的应用.
这种疗法对于严重的,耐治疗的类风湿性疾病可能特别有益.