脊髓动脉栓塞用于门高血压的水出血:一个系统的审查和元分析
Mohadese Ahmadzade1, Shahram Akhlaghpoor2, Hamidreza Rouientan2
1Department of Radiology, Division of Vascular and Interventional Radiology, Baylor College of Medicine, Houston, Texas, Houston, USA.
Emergency radiology
|November 22, 2024
概括
动脉栓塞 (SAE) 能够有效地减少 portal高血压 (PH) 患者的水出血. 这种程序还改善了水等级,增加了血小板计数,显示出有希望的安全性和有效性.
科学领域:
- 干预性放射学 干预性放射学
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 门高血压 (PH) 经常导致胃食道静脉,这是危及生命的出血的主要原因.
- 动脉栓塞 (SAE) 是一种新兴的内血管技术,用于管理PH的并发症.
研究的目的:
- 系统地审查和元分析SAE在治疗PH的继发性水出血中的疗效和安全性.
- 阐明SAE在PH患者整体管理中的作用.
主要方法:
- 一个系统的审查和元分析,遵循PRISMA标准.
- 在EMBASE,PubMed,Scopus和Web of Science数据库中搜索到2024年4月14日.
- 包括对PH的水出血的SAE的观察和临床研究;用于元分析的随机效应模型.
主要成果:
- 分析了18项涉及531名患者的研究.
- SAE显著减少了水出血 (RD = -0.86; p < 0.001).
- 在26%的患者中,发生了完整的水解消,其中78%的患者表现出改善的水等级. 血小板数显著增加 (SMD = 1.15; p < 0.001). 整体并发症率很低.
结论:
- SAE是一种有效和安全的治疗方法,用于PH的水出血.
- 该程序导致出血显著减少,水等级改善,血小板数量增加.
- 在PH并发症的管理中,SAE代表了一种有价值的治疗选择.
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