相关实验视频

Updated: Jun 6, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
07:08

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

7.2K

使用 APOD 预测失序链接器

Zhenling Peng1,2, Haiyan Wu3, Yuxian Luo3

  • 1Research Center for Mathematics and Interdisciplinary Sciences, Shandong University, Qingdao, China. 202199900018@email.sdu.edu.cn.

Methods in molecular biology (Clifton, N.J.)
|November 22, 2024
PubMed
概括

准确预测内在无序链接器 (DLs) 对于理解蛋白质功能至关重要. 新的DLs准确预测器 (APOD) 方法及其Web服务器为此任务提供了必要的工具.

关键词:
无序的链接器内在的混乱是内在的混乱.本质上是无序的蛋白质.机器学习 机器学习支持矢量机器的支持矢量机器.网络服务器的Web服务器.

更多相关视频

Expression Analysis of Mammalian Linker-histone Subtypes14:40

Expression Analysis of Mammalian Linker-histone Subtypes

Published on: March 19, 2012

13.8K
A Protocol for Computer-Based Protein Structure and Function Prediction16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

68.5K

相关概念视频

Cytoskeletal Linker Proteins - Plakins01:09

Cytoskeletal Linker Proteins - Plakins

Plakins are large proteins with binding domains for microtubules, microfilaments, intermediate filaments, and membrane-associated protein complexes at cell junctions. Plakin functions are evolutionarily conserved and are primarily involved in organizing the different components of the cytoskeleton by crosslinking them to each other and connecting them to the cell-matrix and cell adhesion complexes. They are also known to interact with signal transducers, serve as scaffolds for signaling...
2.3K
Ligand Binding and Linkage00:49

Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence...
4.8K
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
17.7K
Mismatch Repair01:36

Mismatch Repair

Overview
39.9K
Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
6.8K