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Updated: Jun 6, 2025

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons
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Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons

Published on: April 3, 2014

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单胺转运器无处不在和向内开放的构造协同最大限度地提高了转运器内细胞化

Tatiana Sorkina1, Tarique Bagalkot1, Mary Hongying Cheng2

  • 1Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Science advances
|November 22, 2024
PubMed
概括

像安非他胺这样的基质会触发多巴胺转运体 (DAT) 的依赖蛋白激酶C (PKC) 的无化和内细胞化. 这个过程涉及形状变化和传送器运动,影响神经元信号传递.

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