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在患有骨骨折的老年患者中,系统性免疫炎症指数和2年全因死亡率

Shuhuai Tan¹, Yu Jiang¹, Kaihua Qin¹

¹Medical School of Chinese PLA, Beijing, China, 100853; Department of Orthopedics, General Hospital of Chinese PLA, Beijing, China, 100853.

Archives of gerontology and geriatrics

|November 22, 2024

概括

系统性免疫炎症指数 (SII) 与老年关节骨折患者死亡风险较高有关. 较高的SII水平表明关节骨折手术后2年死亡率增加.

科学领域:

老年医学老年医学
外科手术的结果
炎症生物标志物炎症生物标志物

背景情况:

关节骨折是老年人患病和死亡的一个重要原因.
确定可靠的死亡率预测因素对于优化患者护理和结果至关重要.

研究的目的:

为了研究系统性免疫炎症指数 (SII) 与患有部骨折的老年患者2年全因死亡率之间的关联.

主要方法:

一项队列研究包括2766名65岁以上的关节骨折患者接受手术.
使用中性粒细胞,血小板和淋巴细胞计数来计算SII.
患者被分为低,中,高SII组;使用Cox回归来评估2年全因死亡率.

主要成果:

与低SII组相比,高SII组的两年全因死亡率 (144.3每1000人年) 显着更高.
高SII组的患者死亡风险增加1.47倍 (95%CI:1.07-2.01) 与低SII组相比.
在增加SII水平和死亡风险之间观察到一个显著的趋势 (P=0.010).

结论:

系统性免疫炎症指数 (SII) 是老年关节骨折患者2年全因死亡率的重要预测指标.
升高的SII水平可能有助于识别患有部骨折手术后死亡风险较高的患者,有助于风险分层和管理.

关键词:

部骨折部骨折部骨折死亡率死亡率死亡率风险因素风险因素风险因素系统性免疫炎症指数

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