openBF:一个开源的有限体积1D血流溶解器.
I Benemerito1,2, A Melis3, A Wehenkel4
1INSIGNEO Institute for in-silico medicine, University of Sheffield, Sheffield, United Kingdom.
Physiological measurement
|November 22, 2024
概括
openBF是一个新的开源计算库,用于模拟心血管系统中的血液流动动力学. 它可以快速提供准确的预测,有助于心血管生物力学研究.
科学领域:
- 生物医学工程 生物医学工程
- 计算流体动力学的流体动力学.
- 心血管生理学心血管生理学
背景情况:
- 计算模拟对于获得心血管生物力学中的生理数据至关重要.
- 非侵入性测量限制需要先进的模拟工具.
研究的目的:
- 介绍openBF,一个用于模拟血液动态的新型计算库.
- 为心血管系统建模提供可访问和高效的工具.
主要方法:
- 用于动脉系统的一维粘弹性模型.
- 在出口处将动脉模型与零维的风箱模型配对.
- 使用有限体积方法来解决方程,在 Julia.中实现.
主要成果:
- 开放BF表现出与现有软件在各种规模的优秀协议,从单个动脉到虚拟群体.
- 实现模拟的低计算时间.
- 通过使用文献数据的多规模研究来验证.
结论:
- openBF在短时间内提供准确的血液动态预测.
- 该库很容易安装,使用和部署在多个平台上.
- 积极维护和开源,促进社区在生物力学方面的贡献.
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