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Updated: Jun 6, 2025

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells
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癌细胞通过不同的机制限制逆转移素表达的免疫性

Siyu Sun1, Eunae You2, Jungeui Hong3

  • 1Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Immunity
|November 22, 2024
PubMed
概括

癌细胞通过控制免疫刺激重复元素来适应炎症信号. 胰腺癌细胞使用LINE-1或ADAR1来减少双链RNA,减轻抗瘤免疫力并促进生长.

关键词:
在 ADAR1 中,ADAR1 是在Tp53的Tp53癌症的演化 癌症的演化癌症 免疫力 免疫力倒置的阿卢斯 (Alus) 是一个倒置的阿卢斯.它们是逆转移子.瘤免疫的微环境

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