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Updated: Jun 6, 2025

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
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编码区域中的m6A位点触发了转化依赖的mRNA衰变

You Zhou1, Miona Ćorović2, Peter Hoch-Kraft2

  • 1Buchmann Institute for Molecular Life Sciences (BMLS) & Institute of Molecular Biosciences, Goethe University Frankfurt, 60438 Frankfurt a.M., Germany; Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

Molecular cell
|November 22, 2024
PubMed
概括

在信使RNA编码序列中的N6-Methyladenosine (m6A) 触发了一种称为CDS-m6A衰变 (CMD) 的新衰变途径. 这一过程依赖于翻译,迅速降解转录,影响基因表达.

关键词:
在P体中,P体是P体.在RNA衰变过程中,RNA衰变.基因组RNA的修饰是RNA的修饰.这就是YTHDF2的原因.编码序列的编码序列.m6A 一个很好的.核糖体的A位点核糖体暂停进行核糖体暂停.翻译翻译翻译翻译翻译翻译

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