在重症监护室入院时的障碍和心脏骤停后的功能结果
Aki Holm1, Jean Baptiste Lascarrou2, Alain Cariou3
1Department of Emergency Care and Services, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Resuscitation
|November 22, 2024
概括
在心脏骤停后的重症监护室 (ICU) 患者中,障碍很常见. 超血症,但不是低血症,与功能表现不佳有关.
科学领域:
- 关键护理医学 关键护理医学
- 电解质不平衡导致的电解质不平衡
- 神经学 神经学
背景情况:
- 障碍经常发生在重症监护室 (ICU) 患者中.
- 从心脏骤停中恢复生命的昏迷患者代表了对电解质干扰的脆弱人群.
- 了解这些疾病的患病率和影响对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定心脏骤停后昏迷中幸存者的ICU入院时,性疾病 (高卡血和低卡血) 的患病率.
- 为了研究这些障碍与心脏骤停后180天的功能结果之间的关联.
- 为了确定特定的水平异常,可以预测神经恢复和长期功能状态.
主要方法:
- 研究人员对四项随机临床试验的数据进行了后期分析.
- 包括那些在自发循环 (ROSC) 恢复后入住ICU的昏迷患者.
- 水平被分类 (正常血量,高血量,低血量),并在180天后使用大脑性能类别尺度评估功能结果. 后勤回归模型用于分析.
主要成果:
- 在1133名患者中,19.5%的患者患有高血症,3.1%的患者在ICU入院时患有低血症.
- 在患有高血症 (81.4%) 和低血症 (68.6%) 的患者中,不利的功能结局比患有正常血症 (58.5%) 的患者更为常见.
- 超血症与较高的不利功能结果几率 (aOR1.85,p=0.02) 有显著的关联,而低血症则没有 (aOR1.36,p=0.53).
结论:
- 障碍,特别是高血症,在昏迷状态的心脏骤停的幸存者中很常见,这些人被送入ICU.
- 住院时的高卡利米亚与180天后不良的功能结果有关.
- 在这个队列中,低血清症与功能结果没有显著的关联.
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