在接受手术的COVID-19患者中肺部并发症和死亡率:一个多中心队列研究
Eva Amzallag1, Thanushka Panchadsaram2, Martin Girard3
1Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.
BMJ open
|November 22, 2024
概括
患有活跃COVID-19的症状患者接受手术时面临更高的肺部并发症和死亡风险. 康复的患者表现出与无症状患者相似的结果,这表明症状状况是手术决定的关键.
科学领域:
- 医学研究 医学研究
- 外科手术的结果
- 传染病流行病学 传染病流行病学
背景情况:
- 在COVID-19阳性患者中进行手术的管理,由于外科手术期间风险增加,存在挑战.
- 加拿大对COVID-19患者手术结果的数据有限.
研究的目的:
- 评估COVID-19在手术中的症状与术后肺部并发症/死亡之间的关联.
- 为了比较康复和无症状COVID-19患者之间的结果.
- 探索恢复时间对手术结果的影响.
主要方法:
- 在北克省七家医院进行多中心观察队列研究.
- 包括活跃或已康复的COVID-19的成年外科患者 (2020年3月至2021年4月).
- 使用多变量逻辑回归和考克斯模型进行分析.
主要成果:
- 症状活跃的COVID-19患者患肺部并发症 (OR 3.19) 和医院死亡率 (HR 3.67) 的风险明显更高.
- 在康复的COVID-19患者中,没有观察到康复时间的显著影响.
- 康复患者的术后结果与无症状患者的结果相似.
结论:
- 症状状态是COVID-19阳性患者手术决策的关键因素.
- 优化外科护理需要考虑患者的COVID-19症状状态.
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