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Updated: Jun 6, 2025

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
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Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel

Published on: September 8, 2017

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多倍体癌细胞显示化学疗法耐药性的标志

Michael J Schmidt1,2, Amin Naghdloo1, Rishvanth K Prabakar1,3

  • 1Convergent Science Institute in Cancer, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, USA.

Oncogene
|November 23, 2024
PubMed
概括

大型多倍体癌细胞,被确定为带有基因组含量增加 (CTC-IGC) 的循环瘤细胞,与晚期前列腺癌患者的生存率较差有关. 与这些细胞相关的新型RNA和蛋白质标记物可能为克服化疗耐药性和预防癌症复发提供新的治疗点.

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