在抑制想象中的威胁期间,功能连接的个体差异
Marlon Westhoff1, Christoph Vogelbacher1, Verena Schuster1
1Department of Psychology, Philipps-University Marburg, Schulstraße 12, 35037 Marburg, Germany.
Cerebral cortex (New York, N.Y. : 1991)
|November 23, 2024
概括
在威胁抑制过程中,个人的大脑连接模式各不相同. 一些个人表现出较少的连接和更高的焦虑,而另一些人表现出更大的连接和更低的焦虑,揭示出不同的情绪调节途径.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 心理学 心理学 心理学
背景情况:
- 功能性磁共振成像 (fMRI) 研究经常使用人际分析.
- 了解大脑功能的个体差异对于个性化医学至关重要.
研究的目的:
- 在抑制想象的未来威胁期间调查功能性大脑连接的个体变化.
- 识别与情绪调节相关的不同神经通路.
主要方法:
- 利用组代多重模型估计 (GIMME) 和根据54名参与者的fMRI数据进行分组.
- 采用双阶段随机效应元分析方法来分析个体差异.
主要成果:
- 确定了可泛化的大脑连接和独特的,个性化的连接模型,用于威胁抑制.
- 发现了两个子组:一个具有更高的焦虑和更少的连接 (滞后的连接R到LPCC),另一个具有更低的焦虑和更大的连接 (LPCC到vmPFC).
结论:
- 在情绪调节期间的功能连接模式表现出显著的个体差异.
- 这些发现突出了潜在威胁抑制和情绪控制的独特神经机制.
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