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Updated: Jun 6, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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改变IL-6信号传递和结核病风险:一个多祖先的孟德尔类随机化研究

Fergus Hamilton1, Haiko Schurz2, Tom A Yates3

  • 1MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

The Lancet. Microbe
|November 23, 2024
PubMed
概括

通过rs2228145-C测量IL-6信号的减少,因果性降低了结核病的风险. 这表明IL-6抗剂对于治疗结核病可能是有益的,而不是有害的.

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Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish07:00

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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