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Updated: Jun 6, 2025

Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts
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通过ACSL4介导的ZIP7-VDAC3相互作用调节了在PFOS暴露下肝细胞中的内细胞网膜-线粒体铁转移

Peiyao Liang1, Kefan Tian1, Wei Yang1

  • 1Department of Environmental and Occupational Health, Dalian Medical University, 9 West Lvshun South Road, Dalian, China.

The Science of the total environment
|November 23, 2024
PubMed
概括

暴露在 perfluorooctane sulfonate (PFOS) 中会导致铁在内分泌网膜 (ER) 和线粒体中积聚. 乙-A合成酶4 (ACSL4) 调解这种铁交叉,影响铁和PFOS毒性.

关键词:
长链乙烯基-CoA合成酶家族成员4 4细胞内膜网膜中的铁.线粒体铁是线粒体中的铁.perfluorooctane 硫酸盐的使用情况

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