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Updated: Jun 27, 2026

Single Cell Transcriptional Profiling of Adult Mouse Cardiomyocytes
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单细胞RNA测序识别了高等级心脏全移植血管病变中独特的细胞特异性基因表达特征

Kaushik Amancherla1, Kelly H Schlendorf2, Nelson Chow2

  • 1Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN; Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, TN; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
|November 23, 2024
PubMed
概括

单细胞分析揭示了心脏全移植血管病变 (CAV) 中不同的基因表达模式,为新的诊断生物标志物和有针对性的疗法提供了潜力,以改善心脏移植结果.

关键词:
生物标志物 生物标志物心脏异体移植血管病变 心脏异体移植血管病变基因表达 基因表达心脏移植手术的心脏移植手术的心脏移植手术单细胞RNA测序的测序方法

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Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...