SARS-CoV-2ACE2

Pisit Ubonsri1, Jiraporn Panmanee1, Ittipat Meewan1

  • 1Institute of Molecular Biosciences, Mahidol University, Salaya, Nakhon Pathom, Thailand.

概括

研究人员确定了两个,Trx-RB9和Trx-RB10,它们与SARS-CoV-2受体结合域 (RBD) 的保留区域结合,跨变体. 这些可以通过阻断ACE2与Omicron变种尖端蛋白结合来抑制病毒的进入.

相关概念视频

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Indirect-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
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Indirect-Acting Cholinergic Agonists: Mechanism of Action

Indirect-acting cholinergic agonists work by interacting with an enzyme called acetylcholinesterase (AChE) in the synaptic cleft. They can be reversible or irreversible inhibitors and have different effects on the enzyme.
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