更多关于COVID-19患者的深层血瘤:案例系列
K Lipatov1, E Komarova1, E Solov'eva1
1Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Russian Federation.
Georgian medical news
|November 24, 2024
概括
COVID-19可能会导致血液凝固的危险失衡,导致血栓形成和严重出血. 这项研究强调了患者的深层血瘤的发生,使感染复杂化并增加死亡风险.
科学领域:
- 医学 医学 医学 医学 医学
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
背景情况:
- 感染COVID-19可能会破坏血液凝固系统.
- 这种失衡的确切性质,无论是血栓形成还是出血,仍然不清楚.
- 在COVID-19患者中,越来越多地报告了深层血液瘤,需要进一步调查.
研究的目的:
- 研究住院COVID-19患者血液瘤形成的特征和结果.
- 分析COVID-19感染期间与血液瘤发展相关的凝血状态和死亡率.
主要方法:
- 在2020年10月至2021年1月期间,对7名COVID-19患者进行观察,这些患者在2020年10月至2021年1月期间出现了血液瘤.
- 使用SOFA和Caprini尺度评估患者的严重程度,并使用治疗剂量的纳德罗巴林治疗.
- 诊断成像 (超声波,CT) 和凝血图的分析,包括D-二次体水平.
主要成果:
- 七名患者 (2.1%的住院患者) 患有血腫,其中5例深層血腫高達340毫升.
- 血液瘤发病的中位时间为7天;3名D-二次数>4000 ng/ml的患者患有肺动脉血栓形成的致命结局.
- 血液瘤患者的死亡率为42.9%,明显高于医院平均水平的7.1%.
结论:
- COVID-19的特点是凝血失衡,包括血栓和出血并发症.
- 深层血液瘤是严重的COVID-19的一个不明确的表现,严重的COVID-19显著恶化了患者的预后.
- 这些发现强调了COVID-19感染带来的复杂的静血挑战.
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