光学连贯断层扫描作为评估脑静脉血栓症治疗反应的辅助工具:一项前性的纵向研究
Guduru Sravanthi1, Rajani Battu2, Mohammed Shereef Pallimalil1
1Department of Neurology, National Institute of Mental Health & Neuro Sciences, Hosur Road, Bangalore 560029, Karnataka, India.
概括
光学连贯断层扫描 (OCT) 可以量化脑静脉血栓 (CVT) 患者的 papilledema. 周 papillary 胆道和视网膜神经纤维层厚度与治疗显著下降.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 乳头,是脑内血压升高 (ICP) 的并发症,在脑静脉血栓形成 (CVT) 中经常观察到.
- 使用光学连贯断层扫描 (OCT) 来定量评估 papilledema 对于监测疾病进展和治疗疗效至关重要.
研究的目的:
- 在CVT患者中通过使用OCT测量周周毛囊胆道厚度 (ChT) 和周周毛囊视网膜神经纤维层厚度 (RNFLT) 来定量评估毛囊.
- 评估CHT和RNFLT在CVT患者治疗和随访期间的变化.
主要方法:
- 一项前性纵向研究,涉及30名CVT患者和年龄/性别匹配的健康对照.
- 超越国土地区的RNFLT和ChT测量是在提交,释放和释放两个月后进行的.
- 对CVT患者和对照人群之间的测量结果进行比较,并评估CVT组内随着时间的推移发生的变化.
主要成果:
- 在46.66%的CVT患者中,乳头发疹存在.
- 与对照组相比,CVT患者表现出显著增加的周周毛囊RNFLT和CHT.
- 在2个月的随访期间,在CVT患者中观察到周周毛囊RNFLT和CHT的显著减少.
结论:
- 在CVT患者中,随着治疗,RNFLT和ChT测量显著下降.
- 海洋和海上国家/地区作为一个有价值的工具,客观地评估与CVT相关的 papilledema 治疗反应.
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