不要破坏 (血液) 银行:在全血计划中,浪费可以被最小化吗?
Jordan Lilienstein1, Debra Lowry1, Andrea Long1
1UCSF Fresno Department of Surgery, Community Regional Medical Center, 2823, Fresno St - 1st Floor, Fresno, CA, 93721-1234, USA.
American journal of surgery
|November 24, 2024
概括
将老化全血 (WB) 转换为红细胞单位 (RBC) 可以最大限度地减少创伤护理中的血液浪费. 与组分疗法相比,这种策略显示了类似的患者结果和更平衡的输血比率.
科学领域:
- 创伤护理 创伤护理
- 输血医学 输血医学
- 血液银行 血液银行
背景情况:
- 全血 (WB) 的浪费是其在创伤复苏中的使用的一个重要障碍.
- 将老化的WB转化为红细胞 (RBC) 单位提供了一个减少浪费的潜在解决方案.
研究的目的:
- 评估将老化的WB转换为红细胞的可行性.
- 在创伤患者中比较WB和RBC输血之间的血液浪费和患者结果.
主要方法:
- 一级创伤中心血库记录的回顾性审查 (8/2020 - 3/2023).
- 对创伤激活患者的分析,这些患者在抵达后4小时内接受了WB或RBC.
- 血液浪费率和临床结果的比较.
主要成果:
- 对WB和O型RBC的可比浪费率 (0.7%对0.5%).
- 677个WB单位输血;668个转换和输血作为RBC,浪费最小 (9个单位).
- 接受WB治疗的患者的输血比率更为平衡,结果与组分疗法 (COMP) 相似.
结论:
- 将衰老的WB转换为红细胞显著减少了血液浪费.
- 这种转化策略的患者结果与组分疗法相提并论.
- 使用转换的WB可以改善创伤复苏中的输血平衡.
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