[关于女性夫妇的精子捐赠请求的法国第一份数据]
Lina Abdiche1, Diane Rivet-Danon1, Clémence Farabet-Demarquette1
1Service de biologie de la reproduction-CECOS, hôpital Tenon, AP-HP, Sorbonne université, 4, rue de la Chine, 75020 Paris, France.
Gynecologie, obstetrique, fertilite & senologie
|November 24, 2024
概括
根据法国2021年生物伦理法,寻求捐精进行医疗辅助生殖 (MAR) 的同性伴侣中的女性表现出与异性伴侣相似的个人资料和怀孕结果.
科学领域:
- 生殖医学 生殖医学
- 生物伦理学生物伦理学
- 卫生社会学 卫生社会学
背景情况:
- 法国2021年的生物伦理法扩大了对未婚妇女和女性夫妇的精子捐赠医疗辅助生殖 (MAR) 的准入.
- 这导致法国生育诊所的精子捐献请求大幅增加.
- 这项研究侧重于经历MAR的女性夫妇的经历.
研究的目的:
- 在新法律出台后,分析同性伴侣中寻求通过精子捐赠获得MAR的女性的个人资料和结果.
- 将这些发现与异性恋夫妇中接受类似手术的女性进行比较.
- 评估法律对不同情侣组合获得生育治疗的影响.
主要方法:
- 在巴黎的性子捐赠中心进行了回顾性,单中心的研究.
- 分析了2021年10月至2022年10月期间参加初次咨询的同性伴侣 (n=117) 和异性伴侣 (n=75) 的女性数据.
- 患者个人资料和ART结果的比较,截至2024年5月.
主要成果:
- 同性伴侣和异性伴侣的女性之间在年龄,卵巢储备或妇科病史上没有显著的差异.
- 同性伴侣的女性饮酒量略高.
- 在接受精子捐赠ART的两组中,累积的早期和持续怀孕率相似.
结论:
- 同性伴侣中的女性表现出与异性伴侣后生物伦理法相似的个人资料和ART结果.
- 这些发现支持对所有接受生育治疗的夫妇类型提供公平的医疗护理.
- 这项研究提供了对法国新生物伦理法对MAR访问的应用的初步见解.
相关概念视频
01:23Infertility in Males
245
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
245
01:41Spermatogenesis
102.1K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.1K
01:43Sex-linked Disorders
100.5K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
100.5K
01:38Fertilization
70.8K
During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
70.8K