寄生囊状结构的存在与认知功能之间的关联
Toshio Ohashi1, Rintaro Ito2,3, Ryo Yamamoto1
1Department of Radiology, Kamiiida Daiichi General Hospital, Nagoya, Aichi, Japan.
概括
位于上斜鼻附近的囊与显著较低的认知功能得分有关. 这些ACES囊可能在认知能力下降中发挥作用,影响微型精神状态检查 (MMSE) 的结果.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 认知科学 认知科学
背景情况:
- arachnoid Cuff Exit Site (ACES) 囊是一种囊状结构,在MRI上被确定在上侧斜附近.
- 以前的报道已经注意到它们的存在,但它们的临床意义,特别是关于认知功能,仍在调查中.
研究的目的:
- 调查ACES囊与认知功能存在的关联.
- 在患有或没有ACES囊的患者中,使用小型精神状态检查 (MMSE) 评分来评估认知功能.
主要方法:
- 对112名患者进行脑部MRI进行痴呆查的回顾性分析.
- 使用曼 - 惠特尼U测试和斯皮尔曼等级相关性,使用ACES囊和无ACES囊的患者之间的MMSE分数和年龄的比较.
- 多变量逻辑回归以确定ACES囊作为较低MMSE得分的独立预测因子.
主要成果:
- 在50.9%的患者中存在ACES囊.
- 患有ACES囊的患者表现出明显较低的MMSE得分 (P < 0.001).
- 存在ACES囊是较低MMSE得分的独立预测因子 (OR = 15.2,P < 0.001).
结论:
- 通过MMSE得分测量,ACES囊的存在与认知功能下降有显著的关联.
- ACES囊可能涉及病理过程,这些过程会对认知功能产生负面影响.
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