评估吸烟习惯对过敏性鼻炎的复杂影响:一项全国跨部门研究
Jae-Min Shin1,2, Yujin Jeong3, Jaehyeong Kim1,2
1Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Clinical and experimental otorhinolaryngology
|November 24, 2024
概括
传统香烟的使用,但不是电子香烟的使用,与韩国成年人过敏性鼻炎 (AR) 的发病率较低有关. 需要进一步的研究来了解吸烟和AR管理之间的复杂关系.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 过敏性鼻炎 (AR) 显著影响生活质量,并造成社会经济成本.
- 讨论了吸烟习惯 (传统香烟[CC]和电子香烟[EC]) 与AR流行率和管理之间的关系.
- 了解这些关联对于公共卫生干预至关重要.
研究的目的:
- 调查吸烟状态 (CC和EC使用) 与韩国成年人AR的患病率和治疗之间的联系.
- 分析韩国国家健康和营养检查调查 (KNHANES) VII (2018) 和VIII (2019-2021) 的数据.
主要方法:
- 在KNHANES的22290名年龄在19岁以上的参与者进行了横截面研究.
- 自我报告的吸烟状况和测量尿中丁水平,用于尼古丁暴露的评估.
- 后勤回归分析,以检查吸烟,丁胺水平和AR患病率/管理之间的关系.
主要成果:
- 单变量分析:EC用户显示AR风险增加35.8%;CC用户显示风险降低27.7%.
- 多变量分析:CC使用者有20.3%的AR风险降低;对于EC使用者没有显著的关联.
- 较高的哥提宁水平 (>500 ng/mL) 与较低的AR患病率相关,特别是在重量使用CC的患者中,但经过对混因子进行调整后,这已经失去了意义.
结论:
- 吸烟状态与韩国人的AR患病率有关.
- 沉重的传统香烟使用表明与AR患病率存在负相关性.
- 电子烟使用对AR的具体影响需要进一步调查.
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