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来自PDL的小细胞外囊的再生潜力

Anahid A Birjandi1, Steven Lynham2, Eva Matalova3

  • 1Centre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, Kings College London, London, UK.

Journal of periodontal research
|November 24, 2024
PubMed
概括

来自牙周带的细胞外囊泡促进Wnt信号传递和骨细胞分化. 这表明,通过增强伤口愈合和矩阵重塑,有可能进行牙周再生疗法.

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...