[在放射治疗后组织肺炎的消化支气管炎:系统性审查和病例报告]
Antoine Ailloud1, Mael Morfin2, Valérie Grangeon3
1Département de radiothérapie, CHU de Saint-Étienne, Saint-Priest-en-Jarez, France; Département de radiothérapie, centre hospitalier de Roanne, Roanne, France; Université de médecine Jacques-Lisfranc, Saint-Étienne, France.
概括
放射治疗后可能发生组织性肺炎 (OP),影响1.4-3%的乳腺癌患者. 关键的风险因素包括年龄,吸烟和被辐射的肺体积,其中皮质类固醇是主要治疗方法.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
背景情况:
- 组织性肺炎 (OP) 是一种具有多种触发因素的炎症性肺部疾病,包括自身免疫性疾病和胸部放射治疗等非传染性原因.
- 放射后有组织性肺炎是一个公认的临床实体,需要与其他肺病理区分开来.
研究的目的:
- 审查有关放射治疗后有组织性肺炎的文献.
- 总结其病因,临床和放射学特征以及治疗策略.
主要方法:
- 对PubMed索引的文章进行了系统审查.
- 搜索术语包括"密码性组织性肺炎"",支气管炎消灭性组织性肺炎 (BOOP) "",非异常组织性肺炎"和"辐射"",放射治疗"",乳腺癌".
主要成果:
- 确定了96篇文章,其中49篇符合选择标准.
- 在乳腺癌患者中,放射治疗后组织性肺炎的发生率小于2.9%.
- 风险因素包括年龄,吸烟和被辐射的肺体积;诊断可能发生在辐射后长达一年.
结论:
- 组织性肺炎影响1.4-3%的乳腺癌放射治疗患者.
- 年龄,吸烟和被辐射的肺体积是显著的风险因素.
- 放射治疗师的意识对于改善患者管理至关重要.
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