在接受心脏手术的患者中,术后狂妄症的风险因素是术后血压变化
Xiao Shen1, Hong Tao1, Wenxiu Chen1
1Department of Critical Care Medicine, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, 210006, Nanjing, People's Republic of China.
BMC anesthesiology
|November 24, 2024
概括
心脏手术后的术后妄 (POD) 与血压变化 (BPV) 有关. 血压的平均真实变化 (ARV) 较高,特别是在手术后,会增加POD的风险. 保持稳定的血压可以防止妄想.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 密集护理医学 密集护理医学
背景情况:
- 妄想是心脏手术后经常出现的神经并发症.
- 了解术后痴呆症 (POD) 的危险因素对于患者的治疗结果至关重要.
- 外科手术期间血压变化 (BPV) 是POD发展的一个潜在的,研究不足的因素.
研究的目的:
- 为了研究术前血压变化 (BPV) 和术后妄 (POD) 之间的关联.
- 确定与心脏外科手术患者POD发病率相关的特定BPV指标.
主要方法:
- 研究了接受心血管重症监护室 (ICU) 的成人心脏手术患者.
- 术后血压变化 (BPV) 用标准偏差 (SD) 和实际平均变化 (ARV) 来量化.
- 妄想评估使用精神状态评估和混乱评估方法 (CAM).
- 进行了LASSO和后勤回归分析,以确定BPV和POD之间的关系.
主要成果:
- POD的发病率为15.0%,平均发病时间在术后第3天.
- 患有POD的患者表现出较低的手术内平均血压和血压ARV.
- 然而,患有POD的患者在术后24小时内表现出显著更高的静脉压,静脉压和平均血压的ARV.
- 在手术期间的血压ARV,中央静脉压的平均值和手术后的静脉血压ARV被确定为POD的独立风险因素.
结论:
- 外科手术期间的平均真实变化 (ARV),特别是手术后的ARV升高,与术后妄想 (POD) 有关.
- 在外科手术期间保持稳定的血压可能是减少心脏手术患者POD发病率的一种策略.
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