睡眠障碍作为品味功能障碍风险的独立预测因素
Rongcai Huang1, Quanyi Zheng2, Juan Dai3
1Department of Stomatology, Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.
BMC oral health
|November 24, 2024
概括
睡眠障碍在40岁以上的成年人中,增加了36%的味觉功能障碍的风险. 虽然睡眠问题改变了口腔微生物组,但它并没有调解这种口味功能障碍的风险.
科学领域:
- 口腔健康 口腔健康
- 睡眠的药物 睡眠的药物
- 微生物组研究的研究.
背景情况:
- 睡眠障碍很普遍,影响整体健康.
- 味觉功能障碍会影响生活质量和营养摄入量.
- 口腔微生物群在感官感知中的作用是一个新兴的研究领域.
研究的目的:
- 检查40岁以上成年人睡眠障碍和味觉功能障碍之间的关联.
- 研究口腔微生物组在这种关系中的潜在调解作用.
主要方法:
- 利用了来自国家健康和营养检查调查 (2011-2014) 的横截面数据.
- 采用回归模型,调整人口变量和共变量.
- 分析了口腔微生物群的多样性,并进行了调解分析.
主要成果:
- 患有睡眠障碍的人患口味功能障碍的风险增加了36% (OR:1.36,p=0.05).
- 睡眠障碍与口腔微生物群多样性降低有关 (OTUs,Shannon-Wiener,Faith PD;p<0.05).
- 口腔微生物组没有调解睡眠障碍和味觉功能障碍之间的关系 (p>0.05).
结论:
- 睡眠障碍独立地与更高风险的味觉功能障碍有关.
- 口腔菌群的变化可能导致睡眠障碍患者的味觉功能障碍.
- 需要进一步的研究来阐明所涉及的精确机制.
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