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皮肤肌炎患者的心周动脉淋巴瘤:一个病例报告
Kei Hirose1, Takayuki Katsuyama1, Natsuki Kubota1
1Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Modern rheumatology case reports
|November 25, 2024
概括
本案例研究突出显示了一例罕见的冠状动脉淋巴瘤,该患者被诊断患有抗转录介质因子1-γ抗体阳性皮肤肌炎. pozitron发射断层扫描-计算机断层扫描有助于检测恶性瘤在这个复杂的呈现.
科学领域:
- 类风湿病学 类风湿病学
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
背景情况:
- 抗转录中间因子1-γ (TIF1γ) 抗体阳性皮肤肌炎是一种异常性炎症性肌肉病变.
- 由于癌症风险增加,TIF1γ阳性皮肤肌炎的恶性查至关重要.
- 冠状动脉淋巴瘤是一种非常罕见的恶性瘤,之前与肌肉炎没有任何关联.
研究的目的:
- 报告TIF1γ阳性皮肤肌炎的一个独特病例,由冠状动脉淋巴瘤复杂化.
- 强调先进成像在识别隐性恶性瘤的诊断实用性.
- 讨论管理复发性自身免疫疾病与叠加癌症的挑战.
主要方法:
- 一个60多岁的女性的临床表现,具有特征性皮肤肌炎症状.
- 初始检查包括对比增强计算机断层扫描,内镜和妇科检查.
- 通过骨髓活检和正子发射断层扫描-计算机断层扫描 (PET-CT) 确认诊断.
主要成果:
- 该患者被诊断为TIF1γ阳性皮肤肌炎和间歇性肺炎.
- 最初的恶性查结果为负.
- 尽管接受了免疫抑制疗法,但发生了复发性疾病发作.
- PET-CT检测显示冠状动脉恶性淋巴瘤与疑似系统性转移.
- 尽管接受了化疗,但患者因气泡出血而死亡.
结论:
- 冠状动脉淋巴瘤是一种罕见的实体,其与肌肉炎的关联是前所未有的.
- PET-CT是检测TIF1γ阳性皮肤肌炎中恶性病变的宝贵工具,特别是在复发复发的情况下.
- 这一案例强调了对自身免疫性疾病进行警性瘤监测的重要性.
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