收集时间活动数据以支持暴露评估:系统证据地图协议
Elizabeth A Chatpar1, Iman Habib1, Lori Rosman2
1Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
概括
本研究介绍了一个系统的协议,以绘制时间活动数据 (TAD) 在环境健康研究中如何使用. 它旨在创建一个数据库和证据地图,以指导未来的暴露评估.
科学领域:
- 环境健康科学 环境健康科学
- 暴露科学 暴露科学
- 公共卫生研究 公共卫生研究
背景情况:
- 时间活动数据 (TAD) 量化了人类活动,对于估计环境剂暴露至关重要.
- 现有的文献缺乏对TAD收集方法在环境健康方面的系统性描述.
- 了解TAD收集对于在不同环境中准确评估暴露至关重要.
研究的目的:
- 系统地绘制环境健康文献,收集TAD进行暴露估计.
- 提出TAD的新定义,并确定其收集方法.
- 为研究环境暴露的研究人员创建一个全面的资源.
主要方法:
- 开发基于人口暴露方法 (PEM) 标准的系统证据地图协议.
- 实施详细的搜索策略,针对环境暴露研究.
- 使用代码书和反射日记来进行代的方法改进和数据分类.
主要成果:
- 将制作一个收集TAD研究的开源数据库.
- 一个系统的证据地图将在视觉上表示TAD收集中的模式,趋势和差距.
- 这些发现将突出TAD如何用于估计各种环境暴露.
结论:
- 证据地图和数据库将成为环境健康研究人员的宝贵工具.
- 这项工作将通过确定TAD收藏中的突出主题和具体研究来为未来的研究提供信息.
- 它旨在提高环境健康研究中暴露估计的严谨性和一致性.
更多相关视频
15:00Setup of Consumer Wearable Devices for Exposure and Health Monitoring in Population Studies
Published on: February 3, 2023
3.0K
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
2.5K
相关概念视频
Pharmacokinetic–Pharmacodynamic Relationship: Exposure, Response and Effect
266
The pharmacokinetic-pharmacodynamic (PK-PD) relationship describes the intricate link between drug exposure, efficacy, and toxicity, forming the foundation for optimal dosing regimens. This relationship uses mathematical modeling to characterize drug concentration-effect dynamics, ensuring precise therapeutic outcomes.Exposure represents the pharmacokinetic aspect of the PK-PD relationship, denoting the drug amount that elicits a biological response. It is typically quantified by administered...
266
Hazard Ratio
756
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
For example, in a clinical trial...
756
