新生儿和母亲在出生时维生素D水平之间的关联
Satvik Jaiswal1, Utkarsh Bansal1, Ekansh Rathoria2
1Pediatrics, Hind Institute of Medical Sciences, Barabanki, IND.
Cureus
|November 25, 2024
概括
母亲和新生儿维生素D缺乏是常见的. 这项研究发现,母亲和婴儿在出生时的维生素D水平之间存在强烈的积极联系,这凸显了怀孕期间查和补充维生素D的必要性.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿科学 新生儿科学
- 营养科学 营养科学
背景情况:
- 维生素D对于母亲和婴儿的骨和外骨健康至关重要.
- 维生素D缺乏症在母亲和新生儿中普遍存在.
- 了解母亲和新生儿维生素D水平之间的关系对于围产期健康至关重要.
研究的目的:
- 调查出生时母亲和新生儿维生素D水平之间的关联.
- 为了确定母婴二合体中维生素D缺乏症的患病率.
- 探索与孕妇及其新生儿维生素D水平相关的因素.
主要方法:
- 一项描述性观察性研究,涉及102名母婴双在三级中心.
- 产后采集母亲静脉血液和带血样本,以测量维生素D水平.
- 分析使用描述性统计,奇平方测试和皮尔森的R,显著程度为p<0.05.
主要成果:
- 观察到维生素D缺乏的高患病率:92.2%的母亲和98%的新生儿.
- 平均母亲和新生儿维生素D水平分别为16.20 (8.29) ng/mL和15.23 (7.06) ng/mL.
- 在母亲和新生儿维生素D水平之间发现了显著的正相关性 (皮尔森R=0.676,p<0.0001),受母亲年龄,BMI和穿衣类型的影响.
结论:
- 在母亲和新生儿中存在很高的维生素D缺乏率.
- 孕产妇和新生儿的维生素D水平有很强的相关性.
- 建议进行常规的维生素D查和产前补充剂,以减轻母婴二合体的缺乏.
相关概念视频
Role of Skin in Vitamin D Synthesis
5.0K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.0K
Vitamins
563
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
563
Development of Immunocompetence
288
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
288
Role of Vitamins in Maintaining Bone Health
3.2K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.2K
Rh Blood Group
1.3K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.3K
Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K


