无人机登记:对亚洲晚期前列腺癌患者的基线数据的最终分析
Dingwei Ye1, Ravindran Kanesvaran2, Edmund Chiong3
1Fudan University Shanghai Cancer Center, Shanghai, China.
Therapeutic advances in medical oncology
|November 25, 2024
概括
联合打击前列腺癌 (UFO) 登记突出了亚洲前列腺癌 (PC) 负担的增加. 对新型治疗方法的限制影响了亚洲PC患者的生活质量和结果.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 临床研究 临床研究
背景情况:
- 在亚洲国家,前列腺癌 (PC) 发病率正在上升.
- 亚洲PC的流行病学,治疗和结果的记录不足.
- 需要了解该地区PC的当代格局.
研究的目的:
- 为了描述抗击前列腺癌 (UFO) 登记册中的患者的人口和疾病特征.
- 为亚洲前列腺癌患者的治疗模式和临床结果提供见解.
主要方法:
- 一项涉及八个亚洲国家/地区PC患者的多国纵向观察性研究.
- 从2015年9月到2020年9月,连续招募高风险局部 (HRL),非转移性生化复发或转移性PC的患者.
- 对患者进行长达5年的随访,以评估结果.
主要成果:
- 该UFO登记册包括3635名患者:425名HRL,389名非转移性复发,2821名转移性PC.
- 转移性PC患者在入学时表现出明显更差的生活质量得分.
- 治疗决策主要以指导方针和疾病进展为指导;新兴激素治疗的使用是有限的.
结论:
- 该UFO注册表提供了关于亚洲PC患者特征,治疗和结果的全面视图.
- 亚洲有很大的未满足的需求,需要改善获得新型治疗剂的机会.
- 提高获得新药的机会可能会改善亚洲PC患者的生活质量和临床结果.
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