2021-2022年沙特阿拉伯沙特阿拉伯利雅得地区婚前查计划的结果:一个横截面研究
Saad N Al Zuayr1,2, Suha M Sulimani3, Eman E Abd-Ellatif1,4
1Field Epidemiology Training Program, Deputyship of Public Health, Ministry of Health, Riyadh, KSA.
Journal of Taibah University Medical Sciences
|November 25, 2024
概括
这项研究研究了状细胞病 (SCD) 和沙特阿拉伯王国利雅得传染病的流行率. 性别是SCD,HIV,HBV和HCV病例的重要因素,强调了有针对性的公共卫生战略的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 遗传学 遗传学 是一个
背景情况:
- 婚前查计划对于识别遗传疾病和传染病至关重要.
- 了解疾病患病率和人口统计学关联对于有效的公共卫生干预至关重要.
研究的目的:
- 调查状细胞病 (SCD),β-血病,人类免疫缺陷病毒 (HIV),乙型肝炎病毒 (HBV) 和乙型肝炎病毒 (HCV) 的流行情况.
- 确定这些疾病在沙特阿拉伯王国 (KSA) 利雅得的人口学关联.
主要方法:
- 追溯的横截面研究设计,利用国家数据从健康婚姻计划在利雅得.
- 数据包括人口统计信息,实验室结果 (血液学和血清学) 和诊断状态.
- 统计分析包括K-S测试数据正常性和多重逻辑回归来确定几率比率 (OR) 与95%置信区间 (CI).
主要成果:
- 在2021年和2022年期间,共有916295名参与者接受了查.
- 确定了196例状细胞病 (SCD) 和4610名携带者,以及1069例感染性疾病 (HIV,HBV,HCV) 的阳性病例.
- 性别被确定为与SCD,HIV,HBV和HCV相关的显著人口因素.
结论:
- 研究结果强调了婚前查和遗传咨询计划对于早期识别和干预的重要性.
- 有针对性的公共卫生战略对于减少遗传疾病和传染病负担至关重要.
- 建议未来进行纵向研究,以监测疾病趋势并评估预防措施的影响.
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