童年不良经历与肠-大脑相互作用障碍之间的关系
Julia Fritz1,2,3, Rachel Coffey2, Jackson Bloch1
1Maine Medical Partners Pediatric Gastroenterology, Portland, Maine, USA.
Journal of pediatric gastroenterology and nutrition
|November 25, 2024
概括
由不良童年经历 (ACEs) 衡量的更高的童年逆境,与儿童的肠-大脑相互作用障碍 (DGBI) 诊断增加有关. 焦虑在很大程度上调解了这种联系,突出了对综合护理方法的需求.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 儿童心理学 儿童心理学
- 神经胃肠病学 神经胃肠病学
背景情况:
- 肠-大脑相互作用障碍 (DGBI) 涉及复杂的心理社会,生理和早期生活因素.
- 儿童不良经历 (ACE) 与成人DGBI有关,但对儿童的关系不太清楚.
- 在儿科患者中,ACE和DGBI都很常见.
研究的目的:
- 调查儿童ACE得分和DGBI诊断之间的关联.
- 探索焦虑在儿童患者中ACE和DGBI之间的关系中扮演的调解角色.
主要方法:
- 3-18岁患者的回顾性审查,记录了ACE得分.
- 三组的比较:没有儿科胃肠病学 (GI) 转诊,GI转诊与DGBI诊断,和GI转诊没有DGBI诊断.
- 基于ACE分数和焦虑的调解效应来确定DGBI诊断的可能性的统计分析.
主要成果:
- 在897次儿科胃肠道咨询中,44.7%的结果是DGBI诊断.
- 每个额外的ACE都增加了1.09倍的DGBI诊断的几率 (p ≤ 0.001).
- 在ACE和DGBI之间的关系中,焦虑诊断占73% (p = 0.012).
结论:
- 在儿科胃肠道护理中,较高的ACE得分与增加的DGBI诊断相关.
- 焦虑起着重要的调解作用,建议焦虑管理作为一个关键的干预点.
- 研究结果支持针对DGBI儿童的多学科干预措施,整合初级和专科护理.
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