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Updated: Jun 6, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
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对氨酸还原酶1和2的进化分析表明,NQO2进化为伪酶的功能

Faiza Islam1, Nicoletta Basilone1, Vania Yoo1

  • 1Department of Biochemistry, University of Western Ontario, London, Ontario, Canada.

Protein science : a publication of the Protein Society
|November 25, 2024
PubMed
概括

昆还原酶NQO1和NQO2进化出了不同的辅基质偏好. NQO1提高了NADH/NADPH的效率,而NQO2降低了它,揭示了关键的进化适应.

关键词:
酸 (NAD) 酸 (P) 酸在 NQO1 和 NQO2 的情况下,二基胺胺的辅因子是二基胺的辅因子.弗拉文的氧化还原开关黄毒素 (flavodoxin) 是一种可怕的药物.类似的酶进化过程.氨酸减少酶可以减少氨酸减少酶.

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