童年不良经历对美国成年人喘严重性的影响
Chukwuemeka E Ogbu1, Ioannis Stouras2, Chisa O Oparanma3
1Department of Internal Medicine, Cape Fear Valley Health, Fayetteville, NC 28304, USA.
Medical sciences (Basel, Switzerland)
|November 25, 2024
概括
儿童不良经历 (ACE) 与美国成年人,特别是女性喘严重程度的增加有关. 通过早期干预来减少ACE可能有助于管理成人喘.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 环境健康 环境健康
背景情况:
- 儿童不良体验 (ACE) 和它们与美国成年人喘严重程度的关联仍然未得到充分研究.
- 在ACEs-喘严重程度联系的性别差异需要进一步调查.
研究的目的:
- 为了确定美国成年人中喘严重程度的患病率.
- 调查ACE和喘严重程度之间的关联,包括性别特异性影响.
主要方法:
- 使用2019-2020年行为风险因素监测系统 (BRFSS) 喘回调调查 (ACBS) 数据进行的横截面研究.
- 分析了22934名患有喘的美国成年人,评估了11个ACE变量和喘严重程度 (间歇性与持续性).
- 权重后勤回归模型用于检查关联,控制混因素和按性别分层.
主要成果:
- 持续性喘影响45.3%的美国成年人患有喘.
- 较高的累积ACE得分与持续性喘的几率增加相关 (aOR=1.054每单位增加).
- 在特定的ACE (例如,性虐待,父母离婚,家庭滥用酒精) 和持久性喘之间发现了显著的关联,在女性中观察到更强烈的影响.
结论:
- 暴露于ACE与美国成年人,特别是女性持久性喘的几率更高有关.
- 这些发现强调了预防策略和早期干预的必要性,以减轻ACE并可能减少成人喘的严重程度.
- 针对ACE的有针对性的干预措施可能对喘管理和公共卫生至关重要.
相关概念视频
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Asthma-II: Pathophysiology and Classification
2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Asthma: Pathogenesis and Management
351
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
351
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
Antiasthma Drugs: β2-Adrenoceptor Agonists
233
Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
233


