慢性腹:不是一种罕见的维生素B12缺乏的表现
Noreen Adil1, Adil Mehraj2, Jamila Khan1
1Wah Medical College, POF Hospital Wah Cantt-Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|November 25, 2024
概括
维生素B12替代剂有效地治疗缺乏维生素B12的患者的慢性腹. 对大多数参与者来说,补充剂在一周内导致了显著的症状缓解.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 慢性腹影响全球3-15%的人口.
- 定义为>3个便/天或>200克便重量>4周.
- 通常与营养缺乏有关,包括维生素B12.
研究的目的:
- 评估维生素B12替代疗法的疗效.
- 针对慢性腹和确诊的维生素B12缺乏症的患者.
- 在临床环境中研究治疗结果.
主要方法:
- 准实验性研究涉及12-65岁的慢性腹患者.
- 包括血清维生素B12低和叶酸正常的患者.
- 通过腹腔内服维生素B12并监测症状的缓解.
主要成果:
- 亲肠道维生素B12补充剂在76.2%的患者中有效.
- 在所有反应良好的患者中,腹在一周内消失.
- 观察到显著改善,许多患者在<4天内 (p<0.001) 呈现出明显改善.
结论:
- 维生素B12替代剂是慢性腹的可行治疗方法.
- 对于已确诊的维生素B12缺乏症患者有效.
- 补充后观察到的快速症状缓解.
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