抗凝血状态和脑静脉血栓症的结果:来自南印度的一项单中心回顾性研究
Deepak Menon1, Manisha Gupta1, Sangeeth Thuppanattumadam Ananthasubramanian1
1Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bengaluru, Karnataka, India.
Annals of Indian Academy of Neurology
|November 25, 2024
概括
在脑静脉血栓症 (CVT) 治疗中,可能不需要强化抗凝药. 在大多数患者中,低强度抗凝药显示出良好的结果,特别是在可治疗的CVT原因中.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 血栓形成研究研究
背景情况:
- 大脑静脉血栓症 (CVT) 治疗通常涉及抗凝剂.
- 关于CVT中最佳抗凝血强度和持续时间的证据有限.
研究的目的:
- 为了评估抗凝剂在脑静脉血栓症患者的有效性和结果.
- 评估抗凝强度与患者在CVT中的结果之间的关系.
主要方法:
- 在5年的时间里,从204名CVT患者回顾性数据收集.
- 对人口,临床,放射学数据和抗凝血状态 (INR) 的分析.
- 最少6个月的随访,至少记录了三个INR值.
主要成果:
- 患者的平均年龄为34.4岁;95.1%的患者已经进行了CVT.
- 抗凝药 (阿诺库马罗/华法林) 持续平均16个月.
- 治疗范围中的低时间 (INR 2-3:5.1%),次治疗范围中的高时间 (INR 1-1.5:68.7%).
- 在89.7%的患者中获得良好结果;CVT分级表得分预测了结果.
结论:
- 强烈的抗凝血可能不必用于CVT管理.
- 较低强度的抗凝药似乎是有效的,特别是当CVT是由短暂的,可治疗的因素引起时.
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