相关实验视频
Updated: Jun 6, 2025

Cecal Ligation Puncture Procedure
Published on: May 7, 2011
在患有尿路感染的老年患者中,感染性休克的危险因素
Takaaki Tsuchiya1,2, Kenta Taito1, Yui Ota1
1Department of Nephrology and Dialysis, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-Cho, Itabashi, Tokyo, 173-0015, Japan.
Backgrounds:
很少有研究探讨老年尿路感染患者发生感染性休克的危险因素。我们决定 investigate 在老年患者中是否存在类似的风险。
方法:
共纳入1478名因尿路感染住院治疗的老年患者(男性492人,女性986人),年龄均为65岁或以上(平均年龄85.1岁)。通过回顾性分析患者的病历资料,研究了导致这些患者发生感染性休克的相关因素,包括致病病原体及所采用的治疗措施。
结果:
尿路感染合并尿路结石被发现是发生感染性休克的最重要危险因素(p < 0.01)。合并尿路结石的患者更为虚弱,尿液pH值和钙水平更高,并且由耐药菌及罕见细菌引起的感染频率更高。聚类分析显示,在接受碳青霉烯类和/或耐甲氧西林金黄色葡萄球菌(MRSA)药物治疗的患者组中,死亡、感染性休克、尿路结石及虚弱的发生率更高。
结论:
脓毒症休克与中国台湾老年尿路感染患者的高死亡风险相关,尿路结石被确定为发生脓毒症休克的独立危险因素。尿路结石还与衰弱相关,提示预防衰弱可能间接改善继发于尿路感染的脓毒症休克患者的预后。
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