增强对比度的乳房造影可以提高对可疑发现的诊断工作的积极预测值吗? 一个单臂前性研究
Jason Shames1, Adrien Nguyen1, Maria Sciotto1
1Department of Breast Imaging, Thomas Jefferson University, Philadelphia, PA, USA.
与对比度增强的乳房造影 (CEM) 显著提高了可疑乳房发现的积极预测值 (PPV3). 这种增强有助于减少不必要的乳腺活检的数量,提高诊断准确度.
科学领域:
- 乳房成像 乳房成像
- 诊断放射学是指诊断放射学.
- 在瘤学瘤学.
背景情况:
- 数字乳腺图解 (DBT) 和超声波 (US) 是评估可疑乳腺发现的标准.
- 它们的积极预测值 (PPV3) 有局限性,可能导致不必要的活检.
- 增强对比度的乳房显微镜 (CEM) 是一种新兴的乳房损伤评估技术.
研究的目的:
- 在可疑的乳腺发现中评估CEM的正预测值-3 (PPV3) 和负预测值 (NPV).
- 为了确定CEM是否与DBT和US相比提高了诊断准确度.
- 评估CEM在减少不必要的乳腺活检方面的潜力.
主要方法:
- 一项前性研究涉及99名女性,在DBT和/或US上发现异常发现.
- 所有参与者在活检之前都接受了CEM.
- 根据最终的病理学结果计算PPV3和NPV,并使用统计分析进行比较.
主要成果:
- CEM显著增加了PPV3,从38.4%增加到60.3% (P < .01).
- CEM证明了100%的现金价值.
- 添加CEM可以减少36.4%的不必要的活检.
结论:
- 除了诊断工作外,CEM还显著改善了可疑乳腺发现的PPV3.
- CEM显示高的NPV,这表明其在排除恶性瘤中的实用性.
- CEM有可能降低不必要的乳腺活检率.
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